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Search Results for " neuropsychiatric disorders "

8

Compounds

Cat No. Product Name Synonyms Targets
T12998 SR10067 Others , Autophagy
SR10067 is a potent, selective and brain penetrant agonist of Rev-Erbα/β(IC50 of 160 and 170 nM for Rev-Erbβ and Rev-Erbα, respectively),has anxiolytic activity.
T22882 JP1302 Adrenergic Receptor
JP1302 is a selective α2C adrenoceptor antagonist with a Kb value of 16 nM and a Ki of 28 nM for human α2C receptors.JP1302 has antidepressant activity, disrupts the FACT complex and degrades histone H1.JP1302 has been u...
T60060 ACSS2-IN-2 MTB-9655 Fatty Acid Synthase
ACSS2-IN-2 (MTB-9655) is an inhibitor of acyl-CoA synthetase short-chain family member 2 (ACSS2). ACSS2-IN-2 can inhibit ACSS2 activity with an IC50 value of 3.8 nM. ACSS2-IN-2 can be used for the research of several dis...
T13322 VU6005806 AZN-00016130 Others
VU6005806 is a potent positive allosteric modulator (PAM) of muscarinic acetylcholine receptor subtype 4 (M4) (EC50s: 94 nM, 28 nM, 87 nM, and 68 nM for human, rat, dog, and cyno M4, respectively), and used in the study ...
T62133 TRPC5 modulator-1
TRPC5 modulator-1 (Compound 9) is a TRPC5 modulator (IC50<1 nM) that can be used to study neuropsychiatric disorders.
T79430 μ opioid receptor agonist 3 Opioid Receptor
Compound 20, identified as μ opioid receptor agonist 3, is a potent µOR agonist that exhibits an EC50 value of 0.87 nM. It holds promise for research into pain management and neuropsychiatric disorders [1].
T69019 Mecamylamine
Mecamylamine, an orally active, nonselective, noncompetitive antagonist of nAChR (nicotinic acetylcholine receptors), exhibits ganglionic blockade capabilities and can cross the blood-brain barrier. Its applications span...
T80421 CSD-CH2(1,8)-NH2 Opioid Receptor
CSD-CH2(1,8)-NH2 is a selective and competitive kappa-opioid receptor (KOR) antagonist with a K i of 6.8 nM. It inhibits calcium mobilization in dorsal root ganglion (DRG) neurons and antagonizes the antinociceptive effe...
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